Frans Vinberg

Frans Vinberg, PhD

Languages spoken: English

Academic Information

Departments Adjunct - Ophthalmology & Visual Sciences

Frans Vinberg, PhD, is an adjunct research professor at the John A. Moran Eye Center.

Research Statement

Our focus is to study how mammalian photoreceptors function and interact with retinal pigment epithelium (RPE), bipolar and Müller glia cells to enable vision over a wide range of light intensities. The main goal is to understand how the interactions and function of these retinal cells are affected in major blinding diseases, including Retinitis Pigmentosa, Diabetic Retinopathy, and Age-Related Macular Degeneration.

Education History

Graduate Training Helsinki University of Technology
 MSc
Doctoral Training Aalto University School of Science
 DSc
Postdoctoral Fellowship Aalto University School of Science
 Postdoctoral Fellow
Postdoctoral Fellowship Washington University School of Medicine
 Postdoctoral Fellow

Selected Publications

Journal Article

  1. Getter T, Gulati S, Zimmerman R, Chen Y, Vinberg F, Palczewski (2019). Stereospecific modulation of dimeric rhodopsin. FASEB journal, 33(8), 9526-9539. (Read full article)
  2. Vinberg F, Peshenko IV, Chen J, Dizhoor AM, Kefalov V (2018). Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors. The Journal of biological chemistry, 293(19), 7457-7465. (Read full article)
  3. Vinberg F, Palczewska G, Zhang J, Komar K, Wojtkowski M, Kefalov VJ, Palczewski (2019). Sensitivity of Mammalian Cone Photoreceptors to Infrared Light. Neuroscience, 416, 100-108. (Read full article)
  4. Mure LS, Vinberg F, Hanneken A, Panda (2019). Functional diversity of human intrinsically photosensitive retinal ganglion cells. Science (New York, N.Y.), 366(6470), 1251-1255. (Read full article)
  5. Hutto RA, Bisbach CM, Abbas F, Brock DC, Cleghorn WM, Parker ED, Bauer BH, Ge W, Vinberg F, Hurley JB, Brockerhoff S (2020). Increasing Ca2+ in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress. Cell death and differentiation, 27(3), 1067-1085. (Read full article)
  6. Vinberg F, Chen J, Kefalov V (2018). Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors. Progress in retinal and eye research, 67, 87-101. (Read full article)
  7. Vinberg F, Kefalov V (2018). Investigating the Ca2+-dependent and Ca2+-independent mechanisms for mammalian cone light adaptation. Scientific reports, 8(1), 15864. (Read full article)