Education History
Fellowship |
University of Maastricht, Academisch Ziekenhuis (AZM), Dept. of OB/Gyn |
Clinical Fellow |
---|---|---|
Research Fellow |
University of Utah, Department of Pharmaceutics and Pharmaceutical Chemistry, Biomedical Polymers |
Postdoctoral Research Fellow |
Residency |
Universitat zu Köln, Department of Obstetrics and Gynecology |
Resident |
Internship/Residency |
Mount Sinai School of Medicine |
Intern/Resident |
Internship/Residency |
Universitat zu Köln, Department of Obstetrics and Gynecology |
Intern/Resident |
Internship/Residency |
Universitat zu Köln, Department of Visceral and Vascular Surgery |
Intern/Resident |
Professional Medical |
Universitat zu Köln |
MD, PhD |
Professional Medical |
Universitat zu Köln, Medical School |
MD |
Selected Publications
Journal Article
- Taurin S, Yang CH, Reyes M, Cho S, Coombs DM, Jarboe EA, Werner TL, Peterson CM, Jant-Amsbury MM (09/26/2017). Endometrial Cancers Harboring Mutated Fibroblast Growth Factor Receptor 2 Protein Are Successfully Treated With a New Small Tyrosine Kinase Inhibitor in an Orthotopic Mouse Model. Int J Gynecol Cancer.
- Almomen A, Jarboe EA, Dodson MK, Peterson CM, Owen SC, Jant-Amsbury MM (09/01/2016). Imiquimod Induces Apoptosis in Human Endometrial Cancer Cells In vitro and Prevents Tumor Progression In vivo. Pharm Res, 33(9), 2209-17.
- Park H, Cho S, Han YH, Janat-Amsbury MM, Boudina S, Bae YH (2015). Combinatorial gene construct and non-viral delivery for anti-obesity in diet-induced obese mice. J Control Release, 207, 154-62. (Read full article)
- Park H, Cho S, Han YH, Janat-Amsbury MM, Boudina S, Bae YH (2015 Mar 25). Combinatorial gene construct and non-viral delivery for anti-obesity in diet-induced obese mice. J Control Release, 25(207), 154-162.
- Yang CH, Almomen A, Wee YS, Jarboe EA, Peterson CM, Jant-Amsbury MM (2015 Mar 23). An estrogen-induced endometrial hyperplasia mouse model recapitulating human disease progression and genetic aberrations. Cancer Med.
- Almomen A, Cho S, Yang CH, Li Z, Jarboe EA, Peterson CM, Huh KM, Jant-Amsbury MM (2015 Jan 22). Thermosensitive Progesterone Hydrogel: A Safe and Effective New Formulation for Vaginal Application. Pharm Res.
- Theisen ER, Gajiwala S, Bearss J, Sorna V, Sharma S, Janat-Amsbury M (10/9/2014). Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma. BMC Cancer, October(14), 752.
- Abood Okal, Karina Matissek, Stephan Matissek, Robert Price, Mohamed Salama, Margit Maria Jant-Amsbury, and Carol Lim (06/24/2014). Re-engineered p53 Activates Apoptosis In Vivo and Causes Primary Tumor Regression in A Dominant Negative Breast Cancer Xenograft Model. Gene Ther.
- Arauchi A, Yang CH, Cho S, Jarboe EA, Peterson CM, Bae YH, Okano T, Jant-Amsbury MM (2014 May 27). An Immunocompetent, Orthotopic Mouse Model of Epithelial Ovarian Cancer Utilizing Tissue Engineered Tumor Cell Sheets. Tissue Eng Part C Methods.
- Cho S, Sun Y, Jarboe EA, Soisson AP, Dodson MK, Gaffney DK, Peterson CM, Jant-Amsbury MM (Dec 2013). Mucoadhesive hybrid gel improves intraperitoneal platinum delivery. Int J Pharm, 458(1), 148-155.
- Sadekar S, Linares O, Noh G, Hubbard D, Ray A, Jant-Amsbury M, Peterson CM, Facelli J, Ghandehari H (2013). COMPARATIVE PHARMACOKINETICS OF PAMAM-OH DENDRIMERS AND HPMA COPOLYMERS IN OVARIAN-TUMOR-BEARING MICE. Drug Deliv Transl Res, Jun; 1((3)3), 260-271.
- Cho SungPil, Jarboe, Kennedy, Soisson, Dodson, Sun, Janat-Amsbury MM (April 2013). Development and characterization of a syngeneic mouse ovarian cancer model. Anticancer Res, 33(4), 1317-1324.
- Zhang R, Luo K, Yang J, Sima M, Sun Y, Janat-Amsbury MM, Kopecek J (2013). Synthesis and evaluation of a backbone biodegradable multiblock HPMA copolymer nanocarrier for the systemic delivery of paclitaxel. J Control Release, 166(1), 66-74. (Read full article)
- Li Z, Cho S, Kwon IC, Janat-Amsbury MM, Huh KM (2013). Preparation and characterization of glycol chitin as a new thermogelling polymer for biomedical applications. Carbohydr Polym, 92(2), 2267-75. (Read full article)
- Cho S, Sun Y, Soisson AP, Dodson MK, Peterson CM, Jarboe EA, Kennedy AM, Janat-Amsbury MM (2013). Characterizing a syngeneic orthotopic mouse ovarian cancer model system for the evaluation of novel drug delivery systems. Anticancer Res, Apr; 33(4), 1317-24.
- Sadekar S, Ray A, Janat-Amsbury M, Peterson CM, Ghandehari H (2011). Correction to Comparative Biodistribution of PAMAM Dendrimers and HPMA Copolymers in Ovarian-Tumor-Bearing Mice. Biomacromolecules. (Read full article)
- Arnida, Janat-Amsbury MM, Ray A, Peterson CM, Ghandehari H (2011). Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages. Eur J Pharm Biopharm, 77(3), 417-23. (Read full article)
- Sadekar S, Ray A, Janat-Amsbury M, Peterson CM, Ghandehari H (2011). Comparative biodistribution of PAMAM dendrimers and HPMA copolymers in ovarian-tumor-bearing mice. Biomacromolecules, 12(1), 88-96. (Read full article)
- Janat-Amsbury MM, Peterson CM, Kim SW (2009). The role of gene- and drug delivery in women's health--unmet clinical needs and future opportunities. Preface. Adv Drug Deliv Rev, 61(10), 767. (Read full article)
- Montejo M, Werner TL, Gaffney D, Janat-Amsbury MM (Aug. 2009). Current challenges in clinical management of endometrial cancer. Adv Drug Deliv Rev, 61(10), 883-9.
- Hunn J, Dodson MK, Webb J, Soisson AP, Janat-Amsbury MM (Aug. 2009). Endometrial cancer - current state of the art therapies and unmet clinical needs: the role of surgery and preoperative radiographic assessment. Adv Drug Deliv Rev, 61(10), 871-82.
- Janat-Amsbury MM, Yockman JW, Anderson ML, Kieback DG, Kim SW (2006). Combination of local, non-viral IL12 gene therapy and systemic paclitaxel chemotherapy in a syngeneic ID8 mouse model for human ovarian cancer. Anticancer Res, 26(5A), 3223-8. (Read full article)
- Janat-Amsbury MM, Yockman JW, Anderson ML, Kieback DG, Kim SW (2006). Comparison of ID8 MOSE and VEGF-modified ID8 cell lines in an immunocompetent animal model for human ovarian cancer. Anticancer Res, 26(4B), 2785-9. (Read full article)
- Bikram M, Lee M, Chang CW, Janat-Amsbury MM, Kern SE, Kim SW (2005). Long-circulating DNA-complexed biodegradable multiblock copolymers for gene delivery: degradation profiles and evidence of dysopsonization. J Control Release, 103(1), 221-33. (Read full article)
- Janat-Amsbury MM, Yockman JW, Lee M, Kern S, Furgeson DY, Bikram M, Kim SW (2005). Local, non-viral IL-12 gene therapy using a water soluble lipopolymer as carrier system combined with systemic paclitaxel for cancer treatment. J Control Release, 101(1-3), 273-85. (Read full article)
- Janat-Amsbury MM, Yockman JW, Lee M, Kern S, Furgeson DY, Bikram M, Kim SW (2004). Combination of local, nonviral IL12 gene therapy and systemic paclitaxel treatment in a metastatic breast cancer model. Mol Ther, 9(6), 829-36. (Read full article)
- Furgeson DY, Yockman JW, Jant MM, Kim SW (2004). Tumor efficacy and biodistribution of linear polyethylenimine-cholesterol/DNA complexes. Mol Ther, 9(6), 837-45.
- Kurbacher CM, Grecu OM, Stier U, Gilster TJ, Janat-Amsbury MM, Untch M, Konecny G, Bruckner HW, Cree IA (2003). ATP chemosensitivity testing in ovarian and breast cancer: early clinical trials. Recent Results Cancer Res, 161, 221-30.
Review
- Taurin S, Almomen AA, Pollak T, Kim SJ, Maxwell J, Peterson CM, Owen SC, Jant-Amsbury MM (11/15/2017). Thermosensitive hydrogels a versatile concept adapted to vaginal drug delivery. [Review]. J Drug Target, (15), 1-18.
- Janat-Amsbury MM, Gupta KM, Kablitz CD, Peterson CM (2009). Drug delivery for in vitro fertilization: rationale, current strategies and challenges. [Review]. Adv Drug Deliv Rev, 61(10), 871-82. (Read full article)
Book Chapter
- Janat-Amsbury, MM, Bae YH (11/30/2013). Nanotechnology in Cancer. In Michelle A. Rudek, Cindy H. Chau, William D. Figg, Howard L. McLeod (Eds.), Handbook of Anticancer Pharmacokinetics and Pharamcodynamics (pp. 703-730). New York: Springer New York.
Abstract
- Janat-Amsbury MM, Yockman JW, Anderson ML, Kieback DG, Kim SW (2004). Combination of local, non-viral IL-12 gene delivery and systemic paclitaxel treatment in a highly metastatic mouse mammary carcinoma [Abstract]. SGI, Houston, USA.
Newspaper
- Vahrenkamp J, Janat-Amsbury MM, Gertz J (03182018). Utah researchers find cortisol may exacerbate endometrial cancers. Deseret News.
- Janat-Amsbury, MM, Alter O (04/14/2015). University of Utah's researchers’ mathematical models could provide better ovarian cancer treatment outcomes. Salt Lake Tribune.
Video/Film/CD/Web/Podcast
- Vahrenkamp J, Janat-Amsbury MM, Gertz J (03152018). Researchers at Huntsman discover driving force of aggressive endometrial cancer [Web]. Salt Lake City: ABC 4 News. Available: http://www.good4utah.com/news/local-news/researchers-at-huntsman-discover-driving-force-of-aggressive-endometrial-cancer/1045399872.
- Vahrenkamp J, Janat-Amsbury MM, Gertz J (03132018). Surprising Discovery Provides Insights into Aggressive Endometrial Cancers [Web]. Sciencenewsline. Available: http://www.sciencenewsline.com/news/2018031321180033.html.
Patent
- Janát-Amsbury MM, Huh KM, Cho S, Almomen A, Peterson CM (2019). GLYCOL CHITIN BASED THERMOSENSITIVE HYDROGELFOR VAGINAL DELIVERY OF PROGESTERONE. U.S. Patent No. 026389-9088-US01. Washington, D.C.:U.S. Patent and Trademark Office.